Composition:
Calbo ® Jr.: Each chewable tablet contains Calcium Carbonate BP 625 mg equivalent to
250 mg elemental Calcium.
Indications:
Raised calcium requirement for children and adolescents at times of rapid growth,
inadequate intake of calcium in the diet due to malnutrition, prevention and treatment of
osteoporosis, disorders of osteogenesis and tooth formation (in addition to specific
treatment), latent tetany and during pregnancy and lactation.
Dosage and Administration:
Children : 1 tablet daily
Adolescents : 1 – 2 tablets daily
Adults : 2 tablets daily or as directed by the physician
Contraindication:
Hypercalcemia and hyperparathyroidism
Hypercalciuria and nephrolithiasis
Hypersensitivity to any component of this product
Severe renal insufficiency
Concomitant digoxin therapy (requires careful monitoring of serum
calcium level)
Precaution:
When hypercalcemia occurs, discontinuation of the drug is usually sufficient to return
serum calcium concentrations to normal. Calcium salts should be used cautiously in
patients with sarcoidosis, renal or cardiac disease, and in patients receiving cardiac
glycosides. Patients with a history of stone formation should also be recommended to
increase their fluid intake. High doses of Vitamin-D should be avoided during calcium
therapy unless specifically indicated.
Side Effects:
Orally administered Calcium Carbonate may be irritating to the GI tract. It may also
cause constipation. Hypercalcemia is rarely produced by administration of calcium alone,
but may occur when large doses are given to patients with chronic renal failure.
Drug Interaction:
Calcium can reduce the enteral absorption of tetracycline and fluoride preparations, and
an interval of at least 3 hours should therefore be allowed between ingestion of these
medications. Vitamin-D increases enteral absorption of calcium. The intestinal uptake of
calcium maybe reduced by concomitant ingestion of certain foods (e.g. spinach, bran, and
other cereal products, milk and milk products). At high doses and in combination with
Vitamin-D, calcium may decrease the response to Verapamil. In digitalized patients, high
doses of calcium may increase the risk of cardiac arrhythmias.
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