Calorate 400mg 10pcs

Indications:

This medication is used to prevent or treat low blood calcium levels in
people who do not get enough calcium from their diets. To fulfill the calcium deficiency
or meet extra need of calcium, it may be used in conditions like osteomalacia, rickets,
latent tetany, postmenopausal osteoporosis, senile osteoporosis, juvenile osteoporosis,
drug (phenytoin, phenobarbital, or prednisone) Induced osteoporosis, pregnancy and
lactation, premenstrual syndrome (PMS), hypoparathyroidism and hip joint plastic
surgery. Calorate®acts against a number of inflammatory diseases like arthritis,
psoriasis, lupus, spondylitis, various cardiovascular ailments, encephalitis, retinitis,
phlebitis, colitis, and multiple sclerosis. Calorate® helps in controlling weight by
suppressing the habit of frequent appetite of chronic overeaters. It is also beneficial in
reducing the effects of mood swings and is proved to be quite effective in cognitive
enhancement. Calorate® protects the heart by enhancing the efficiency of cardiac
muscles. Recent studies on calcium orotate indicate its potential to minimize the risk of
colon cancer.

Dosage and Administration: As an addition to the daily diet, 2-3 tablets are usually
recommended with evening meal or as directed by health care professional. With the
increase in the amount of calcium, the percentage of absorption decreases. Absorption
of calcium is the highest in doses less than or equal to 500 mg. So, taking more than
1,000 mg/day of calcium from supplements may be beneficial if the total amount is
taken in divided doses in separate times during the day.

Contraindications: Calorate® is contraindicated in conditions like incomplete or
infrequent bowel movements, kidney stone, kidney disease, sarcoidosis, increased
activity of the parathyroid gland, high amount of calcium in urine, high amount of
calcium in the blood, extreme loss of body water.

Drug interactions: Calcium can decrease absorption of the following drugs when taken
together: biphosphonates(e.g., alendronate), quinolone antibiotics (e.g., ciprofloxacin,
levofloxacin), and tetracycline antibiotics (e.g., doxycycline, minocycline), levothyroxine,
phenytoin (an anticonvulsant), and tiludronate disodium (to treat Paget’s disease).
Thiazide-type diuretics can interact with calcium supplements, increasing the risks of
hypercalcemia and hypercalciuria. Both aluminum- and magnesium-containing antacids
increase urinary calcium excretion. Mineral oil and stimulant laxatives decrease calcium
absorption. Glucocorticoids, such as prednisone, can cause calcium depletion and
eventually osteoporosis when they are used for months. Oral contraceptives as well as
estrogen compounds reduce calcium. Anti-inflammatories such as NSAIDs, Aspirin,
Ibuprofen deplete calcium. Corticosteroids deplete calcium.

Side effects: Bloating and swelling in the abdomen are common side effects of calcium
orotate. Loss of appetite, upset stomach, constipation, nausea, vomiting,
unusual weight loss, mood changes, bone/muscle pain, headache, increased
thirst/urination, weakness, unusual tiredness, formation of kidney stones may occur
infrequently.