Brand Name: Clindacin 150
Manufacturer:Â Incepta Pharmaceuticals Ltd.
Indications
Clindacin Capsule and IV/IM Injection: Clindamycin hydrochloride has been shown to be effective in the treatment of the following infections when caused by susceptible anaerobic bacteria or susceptible strains of gram positive bacteria such as Streptococci, Staphylococci and Pneumococci; Upper respiratory infections, Lower respiratory infections, Skin and soft tissue infections, Bone and joint infections, Pelvic infections, Intra-abdominal infections, Septicemia and endocarditis, Dental infections. As an alternative therapy when used in combination with quinine or amodiaquine for the treatment of multi-drug resistant Plasmodium falciporum infection.
Dosage & Administration
Dosage of Clindacin Capsule
Serious Infections: 150 mg – 300 mg every six hours.
More severe infections: 300 mg – 450 mg every six hours.
To avoid the possibility of oesophageal irritation, Clindacin capsules should be taken with a full glass of water.
Dosage of Clindacin IV/IM Injection
Adults: Parenteral (IV/IM Administration): Serious infections due to aerobic gram-positive cocci and the more susceptible anaerobes:
Side Effects
The adverse effects have been reported with the use of clindamycin are- abdominal pain, oesophagitis and oesophagial ulcer, nausea, vomiting and diarrhoea, pruritus, skin rashes, urticaria.
Precautions
Clindacin should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Contraindications
Clindamycin is contraindicated in patients previously found to be sensitive to clindamycin or any of the ingredients of this medicine.
Use in Pregnancy & Lactation
Pregnancy: Pregnancy Category B: Clindamycin crosses the placenta in humans. After multiple doses, amniotic fluid concentrations were approximately 30% of maternal concentrations. Clindamycin should be used in pregnancy only if clearly needed.
Lactation: Clindamycin has been reported to appear in breast milk. Therefore, it is not recommended for nursing mothers if not clearly needed.
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