Brand Name: Clindacin
Manufacturer : Incepta Pharmaceuticals Ltd.
Indication
Clindacin cream is indicated in the treatment of bacterial vaginosis. Clindacin cream can be used to treat non-pregnant women and pregnant women during the second and third trimester.
Dosage And Administration
One applicator full (approximately 5 gram) intravaginally at bedtime for 7 consecutive days. In patients in whom a shorter treatment course is desirable, a 3 day regimen has been shown to be effective.
Side Effects
Clindamycin may results the following side effects. Genital tract: vaginitis, vulvo-vaginal irritation Central nervous system: dizziness, headache, vertigo.Gastro-intestinal: heartburn, nausea, vomiting, diarrhea, constipation, abdominal pain. Dermatological: rash, exanthema. Hypersensitivity: urticaria.
Contraindications
Clindamycin cream is contraindicated in individuals with a history of hypersensitivity to Clindamycin, Lincomycin, or any of the components of this vaginal cream. Clindamycin cream is also contraindicated in individuals with a history of regional enteritis, ulcerative colitis, or a history of \”antibiotic-associated\” colitis.
Precautions
The patient should be instructed not to engage in vaginal intercourse, or use other vaginal products during treatment with this product. This cream contains mineral oil that may weaken latex or rubber products such as condoms or vaginal contraceptive diaphragms. Therefore, use of such products within 72 hours following treatment with Clindacin cream is not recommended.
Clindacin cream is not recommended in children under 12 years of age.
There are no adequate and well-controlled studies in pregnant women during the first trimester of pregnancy. This drug should be used during the first trimester of pregnancy only if clearly needed. There is no restriction to use Clindacin cream during the second and third trimester.
It is not known if clindamycin is excreted in breast milk following the use of vaginally administered Clindamycin phosphate. However, orally and parenterally administered Clindamycin has been reported to appear in breast milk
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