Brand Name: Comet 850
Manufacture: Square Pharmaceuticals Limited.
Comet® 850 : Each film coated tablet contains Metformin Hydrochloride EP 850 mg.
INDICATION AND USAGE
Comet®(Metformin Hydrochloride tablet) is indicated as an adjunct to diet and exercise to improve glycemic control in children and adults with type 2 diabetes mellitus. Comet® XR (Metformin Hydrochloride extended release tablet) is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Diarrhea, nausea, vomiting, flatulence, asthenia, indigestion, abdominal discomfort, headache etc.
Lactic acidosis can occur due to Metformin accumulation during treatment with Metformin. The
reported incidence of lactic acidosis in patients receiving Metformin is very low.
Store below 300 C temperature & keep away from light & moisture. Keep out of the reach of
DOSAGE AND ADMINISTRATION
Dosage of Comet®or Comet® XR must be individualized on the basis of both effectiveness and
tolerance, while not exceeding the maximum recommended daily dose. The maximum recommended daily dose of Comet®is 2550 mg in adults and 2000 mg in pediatric patients (10-16 years of age); the maximum recommended daily dose of Comet® XR in adults is 2000mg. Comet®should be given in divided doses with meals while Comet® XR should generally be given once daily with the evening meal. Comet® XR tablet must be swallowed whole and never be crushed or chewed. Comet®or Comet® XR should be started at a low dose, with gradual dose escalation, both to reduce gastrointestinal side effects and to permit identification of the minimum dose required for adequate glycemic control of the patient.