Fenac 50mg 10Pcs

Indications
Diclofenac sodium tablet, injection or suppository is used to relief all grades of pain and inflammation in a wide range of conditions including:
Arthritic conditions: Rheumatoid Arthritis, Osteoarthritis, Ankylosing spondylitis, Acute gout.
Acute musculoskeletal disorders such as periarthritis (e.g., frozen shoulder), tendinitis, tenosynovitis, bursitis.
Other painful conditions resulting from trauma, including fracture, low back pain, sprains, strains, dislocations, orthopaedic, dental and other minor surgery.
Diclofenac Gel is used for the local symptomatic relief of pain and inflammation in:
Trauma of the tendons, ligaments, muscles and joints, e.g, due to sprains, strains and bruises,
Localised forms of soft tissue rheumatism.
Therapeutic Class
Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Pharmacology
Diclofenac, a phenylacetic acid derivative is a prototypical NSAID. It has potent anti-inflammatory, analgesic and antipyretic actions. It reversibly inhibits the enzyme, cyclooxygenase, thus resulting in reduced synthesis of prostaglandin precursors.

The anti-inflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.
Dosage & Administration
Tablet/Suppository/Gel:
Adults:
Enteric coated tablet: A total of 75-150 mg daily given in two or three divided doses.
Sustained release tablets: One tablet daily, taken whole with liquid, preferably during meal.
Suppositories: 75-150 mg daily in divided doses.
Gel: Depending on the painful site to be treated, 2-4 g gel may be applied 3-4 times daily.
Children:
Enteric coated tablet: 1-3 mg/kg per day in divided doses.
Sustained release tablets: Not recommended.
Suppositories: 1-3 mg/kg body weight in divided doses.

Injection:
Each 3 ml ampoule contains Diclofenac Sodium 75 mg & each 2 ml ampoule contains Diclofenac Sodium 75 mg and Lidocaine Hydrochloride 20 mg .
Adults: One ampoule once (or in severe cases, twice) daily by intramuscular injection.
Renal colic: One ampoule once daily intramuscularly. A further ampoule may be administered after 30 minutes, if necessary. The recommended maximum daily dose of diclofenac is 150 mg, by any route. The recommended maximum daily dose of lidocaine is 200 mg.
Children: In juvenile chronic arthritis, 1-3 mg of diclofenac/kg body wt. daily in divided doses.
Elderly patients: In elderly or debilitated patients, the lowest effective dosage is recommended, commensurate with age and physical status.