Ketozol 60ml

Ketozol shampo in indicated in the treatment of
•Dandruff (Pityriasis capitis)
•Pityriasis versicolor (localized)
•Inflammatory skin condition with greasy, red and scaly areas (Seborrhoeic dermatitis)

Ketoconazole is a broad spectrum synthetic antifungal agent which inhibit the growth of dermatophytes, such as Trichophyton sp., Epidermophyton sp., Microsporum sp., and yeasts, such as Candida sp. and Malassezia sp. (Pityrosporum sp.).

Dandruff (Pityriasis capitis) and Seborrhoeic dermatitis – Twice weekly for 2 – 4 weeks. Pityriasis vesicolor – Once daily for maximum 5 days.
Prophylaxis:
Dandruff (Pityriasis capitis) and Seborrhoeic dermatitis- Once every 1 or 2 weeks. Pityriasis versicolor – Once daily for 3 days during a single treatment course before the summer.

To use the Ketoconazole 2% shampoo, follow these steps:
•Use a small amount of water to wet hair & scalp.
•Apply sufficient shampoo to the hair & scalp.
•Use fingers to rub the shampoo until it forms lather.
•Leave the shampoo on the hair for 5 minutes before rinsing.
•Rinse the hair thoroughly with water.

Reduced absorption with antimuscarinics, antacids, H2-blockers, PPIs and sucralfate. Reduced plasma concentrations with rifampicin, isoniazid, efavirenz, nevirapine, phenytoin. May also reduce concentrations of isoniazid and rifampicin. May reduce efficacy of oral contraceptives. May increase serum levels of CYP3A4 substrates e.g. digoxin, oral anticoagulants, sildenafil, tacrolimus.

It is contraindicated for known hypersensitivity to Ketoconazole or any of the excipients.

Topical treatment with Ketoconazole 2% shampoo is generally well tolerated. As with other shampoos, a local burning sensation, itching or contact dermatitis (due to irritation or allergy) may occur on exposed areas. Oily and dry hair may occur rarely.

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.