Indications
• Eczema unresponsive to weak steroid cream or ointment
• Other inflammatory skin disorders resistant to treatment with weaker steroid creams or ointment
• Psoriasis.
Dosage & Administration
yclobate Cream & Ointment
Adults and children over 1 year:
• Apply sparingly to cover the affected area, and gently rub into the skin. Frequency of application is 2 to 3 times daily according to the severity of the condition. The total dose applied should not exceed 50 g weekly.
• Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient\\\’s condition being reviewed.
• Repeated short courses of Clobetasol may be used to control exacerbationsChildren below 1 year: Under 1 year this preparation is not recommended
Nyclobate Scalp Application
• It should be applied to the affected scalp areas twice daily, once in morning and once at night.
• Total dosage should not exceed 50 ml per week.
• As with other highly active topical steroid preparations, therapy should be discontinued when control is achieved
Children: Under 1 year this preparation is not recommended.Nyclobate Shampoo
• It should be applied to the dry (not wet) scalp once a day to the affected areas only.
• It should be massaged gently into the lesions and left in place for 15 minutes before lathering and rinsing.
• Treatment should be limited to 4 consecutive weeks.
• Total dosage of shampoo should not exceed 50 g per week.
• Under 18 years this preparation is not recommended.
Adults and children over 1 year:
• Apply sparingly to cover the affected area, and gently rub into the skin. Frequency of application is 2 to 3 times daily according to the severity of the condition. The total dose applied should not exceed 50 g weekly.
• Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient\\\’s condition being reviewed.
• Repeated short courses of Clobetasol may be used to control exacerbationsChildren below 1 year: Under 1 year this preparation is not recommended
Nyclobate Scalp Application
• It should be applied to the affected scalp areas twice daily, once in morning and once at night.
• Total dosage should not exceed 50 ml per week.
• As with other highly active topical steroid preparations, therapy should be discontinued when control is achieved
Children: Under 1 year this preparation is not recommended.Nyclobate Shampoo
• It should be applied to the dry (not wet) scalp once a day to the affected areas only.
• It should be massaged gently into the lesions and left in place for 15 minutes before lathering and rinsing.
• Treatment should be limited to 4 consecutive weeks.
• Total dosage of shampoo should not exceed 50 g per week.
• Under 18 years this preparation is not recommended.
Interaction
No hazardous interactions have been reported with use of Clobetasol Propionate.
Contraindications
It is contraindicated in rosacea, acne vulgaris, perioral dermatitis, primary cutaneous viral infections (eg. herpes simplex, chickenpox), otitis externa with a perforated eardrum, hypersensitivity to the preparations. Scalp application is contraindicated in infection of the scalp.
Side Effects
Generally this preparation is well tolerated. However, few side effects after prolonged and intensive treatment may cause local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels, particularly when occlusive dressings are used, or when skin folds are involved.
Pregnancy & Lactation
Pregnancy category C: The safe use of this preparation during pregnancy & lactation has not been established.
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