Paricel 20mg 5pcs

Description
Paricel® is a preparation of Rabeprazole Sodium. It is an antisecretory compound that suppresses
gastric acid secretion by inhibiting the gastric H+, K+ ATPase at the secretory surface of the gastric
parietal cell.
Indications

•  Healing of Erosive or Ulcerative Gastro-Esophageal Reflux Disease (GERD)
• Maintenance of healing of Erosive or Ulcerative Gastro-Esophageal Reflux Disease (GERD)
• Prevention of Relapse of Gastro-Esophageal Reflux Disease (GERD)
• Treatment of Symptomatic Gastro-Esophageal Reflux Disease (GERD)
• Healing of Duodenal & Gastric Ulcers
• Helicobacter pylori eradication to reduce the risk of Duodenal & Gastric Ulcer Recurrence
• Treatment of pathological hypersecretory conditions including Zollinger-Ellison Syndrome

Dosage and administration
Healing of Erosive or Ulcerative Gastro-Esophageal Reflux Disease (GERD): The
recommended adult oral dose is Paricel® 20 mg to be taken once daily for 4 to 8 weeks. For those
patients who have not healed after 8 weeks of treatment, an additional 8 weeks course of Paricel®
20 mg may be considered.
Maintenance of Healing of Erosive or Ulcerative Gastro-Esophageal Reflux Disease
(GERD): The recommended adult oral dose is Paricel® 20 mg to be taken once daily.
Prevention of Relapse of Gastro-Esophageal Reflux Disease (GERD): The recommended adult oral
dose is Paricel® 10 mg to be taken once daily. If needed this dose should be increased to Paricel®
20 mg to be taken once daily.
Treatment of Symptomatic Gastro-Esophageal Reflux Disease (GERD): The recommended
adult oral dose is Paricel® 20 mg to be taken once daily for 4 weeks. If symptoms do not resolve
completely after 4 weeks, an additional course of treatment may be considered.
Treatment should commence at Paricel® 10 mg once daily in patients without esophagitis. If there
is no response, the dose should be increased to 20 mg once daily for four weeks. If symptoms do
not resolve completely after 4 weeks, the patient should be further investigated.
Once symptoms have resolved, subsequent symptom control can be achieved using an on demand
regimen of 10 mg to be taken once daily, when needed.
Healing of Duodenal Ulcers and Gastric Ulcers: The recommended adult oral dose for both
duodenal ulcer and gastric ulcer is Paricel® 20 mg to be taken once daily for a period up to 4
weeks. Most patients with duodenal ulcer heal within 4 weeks.
Some patients with duodenal ulcer may respond to Paricel® 10 mg once daily. A few patients may
require additional therapy to achieve healing.
Most patients with gastric ulcer heal within 6 weeks. However, again a few patients may require an
additional 6 weeks of therapy to achieve healing.
Helicobacter pylori eradication to reduce the risk of Duodenal or Gastric Ulcer
Recurrence: Most patients with gastro-duodenal ulcer or chronic gastritis due to H. pylori infection
should be treated with three drug regimen

Side effects
Most common adverse reactions in adults are pain, pharyngitis, flatulence, infection & constipation
and most common adverse reactions in adolescents are headache, diarrhea, nausea, vomiting, and
abdominal pain.