Neuropathic pain associated with diabetic peripheral neuropathy: The maximum recommended dose of Pregabalin (Prelica®) is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Dosing should begin at 50 mg three times a day (150 mg/day) and may be increased to 300 mg/day within 1 week based on efficacy and tolerability. Post herpetic neuralgia: The recommended dose of Pregabalin (Prelica®) is 75 to 150 mg two times a day, or 50 to 100 mg three times a day (150 to 300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Dosing should begin at 75 mg two times a day, or 50 mg three times a day (150 mg/day) and may be increased to 300 mg/day within 1 week based on efficacy and tolerability. Adjunctive therapy for adult patients with partial onset seizures: Pregabalin (Prelica®) at doses of 150 to 600 mg/day has been shown to be effective as adjunctive therapy in the treatment of partial onset seizures in adults. The total daily dose should be divided and given either two or three times daily. In general, it is recommended that patients should be started on a total daily dose not greater than 150 mg/day (75 mg two times-a day, or 50 mg three times a day). Based on individual patient response and tolerability, the dose may be increased to a maximum dose of 600 mg/day. Management of Fibromyalgia: The recommended dose of Pregabalin for fibromyalgia is 300 to 450 mg/day. Dosing should begin at 75 mg two times a day (150 mg/day) and may be increased to 150 mg two times a day (300-mg/day)-within 1 week based on efficacy and tolerability. Patients who do not experience sufficient benefit with 300 mg/day may be further increased to 225 mg two times a day (450 mg/day).
The most common side effects include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and abnormal thinking.
Pregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components.
Pregnancy: Pregnancy category C. So it should only use if potential benefit justifies the potential risks to the fetus.
It is not known if pregabalin is excreted in human milk; it is, however, present in the milk of rats. Maybe you can give replica panerai watch to your lover. So it should be used in nursing mother only if there is a clear benefit over the risk.
Prelica is predominantly excreted unchanged in the urine, undergoes negligible metabolism in humans (<2% of a dose recovered in urine as metabolites, humans like replica panerai), and does not bind to plasma proteins, its pharmacokinetics are unlikely to be affected by other agents through metabolic interactions or protein binding displacement.
Reviews
There are no reviews yet.