Descriptions:
Rosen 28 contains two active ingredients, Ethinylestradiol and Drospirenone. Ethinylestradiol is a synthetic version of oestrogen and Drospirenone is a synthetic form of progesterone. The hormonal components of Rosen 28 inhibit ovulation by suppressing gonadotropin release. Secondary mechanisms, which may contribute to the effectiveness of Rosen 28 as a contraceptive, include changes in the cervical mucus (which increase the difficulty of sperm penetration) and changes in the endometrium (which reduce the likelihood of implantation).
Drospirenone has antimineralocorticoid activity, counteracting oestrogen related sodium retention. In combination with ethinylestradiol, drospirenone displays a favourable lipid profile with an increase in high-density lipoproteinHDL. Drospirenone exerts antiandrogenic activity and does not counteract the ethinylestradiol-related sex hormone binding globulin (SHBG) increase which is useful for binding and inactivating the endogenous androgens.
Indications:
Prevention of pregnancy
To achieve maximum contraceptive effectiveness, Rosen 28 must be taken in the order directed on the package and at intervals not exceeding 24 hours. Women should be instructed to take the tablets at about the same time every day, preferably after the evening meal or at bedtime. One tablet is to be taken daily for 28 consecutive days. Each subsequent pack is started on the day after the current pack is completed.
1. If you have decided to take Rosen 28 for contraception, wait for your next menstruation begins.
2. From the first day of your menstruation, start taking the first light yellow tablet from the left corner of the top row (with arrow mark) of your Rosen 28 tablet pack.
3. Continue taking one light yellow tablet each day along the arrow mark.
4. After taking 21 light yellow tablets for 21 days, then continue taking one white placebo tablet every day from the last row in the pack for next 7 days.
5. It is most likely that your menstruation will start while taking the white tablets. Do not discontinue taking the white tablets. Taking of the white tablets for 7 days will help you keep your tablet taking routine. If your menstruation does not start during this time, check with your doctor to make sure you are not pregnant.
6. After completing the seven white tablets, start taking light yellow tablets from another Rosen 28 pack and continue taking the tablet as long as you don\’t want to be pregnant.
Management of Missed Tablets
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