Apuldon 15mg 10pcs

Indication

1. Stimulation of gut mobility: Non-ulcer dyspepsia, esophageal reflux, reflux esophagitis & gastritis, diabetic gastroparesis.
2. Prevention and symptomatic relief from acute nausea & vomiting in adults from any cause but especially in cytotoxic therapy & radiotherapy, associated with migraine attacks (in combination with analgesics) and L-dopa and bromocriptine treatment for Parkinsonian patients.
3. Functional dyspepsia.

Dosage & Administration

The recommended oral dose for:
Adults: 10-20 mg every 4-8 hours daily.
Children (2-12 years): 0.2-0.4 mg/kg body weight (0.4-0.8ml paediatric drops/10 kg) every 4-8 hours daily.
Suppository: Adult and child body weight over 35 kg: 60 mg twice daily; child 15-35 kg (nausea and vomiting only): 30 mg twice daily.
Note: Both tablet & suspension should be taken 15-30 minutes before a meal. For acute nausea & vomiting maximum period of treatment is 12 weeks.

Contraindications

Patients with a known allergy to Domperidone or Domperidone Maleate or any inactive ingredient of the product.

Side effects

Apuldon may produce hyperprolactinemia which may cause galactorrhea & breast enlargement, soreness and reduced libido. It may rarely cause dry mouth, thirst, headache, nervousness, drowsiness, diarrhea, skin rash and itching.

Drug interaction

Apuldon may reduce the hypoprolactinemic effect of bromocriptine. The effect of antimuscarinics & opioid analgesics may antagonize Apuldon on GI function.