Presentation
AZ-250 Tablet : Each film coated tablet contains Azithromycin Dihydrate USP equivalent to Azithromycin 250 mg.
AZ-500 Tablet : Each film coated tablet contains Azithromycin Dihydrate USP equivalent to Azithromycin 500 mg.
AZ-250 Capsule : Each capsule contains Azithromycin Dihydrate USP equivalent to Azithromycin 250 mg.
AZ-500 Capsule : Each capsule contains Azithromycin Dihydrate USP equivalent to Azithromycin 500 mg.
AZ Taste Masked Powder for Suspension : After reconstitution each 5 ml contains Azithromycin Dihydrate USP equivalent to Azithromycin 200 mg.
Pharmacology
AZ contains Azithromycin Dihydrate USP an azalide, a subclass of macrolide antibiotics, for oral administration. Following oral administration, Azithromycin is rapidly absorbed and widely distributed throughout the body. Azithromycin acts by binding to the 50s ribosomal subunit of susceptible microorganisms and thus interfering with microbial protein synthesis. Azithromycin is active against both Gram-positive and Gram-negative microorganisms.
Indication
AZ is indicated in lower respiratory tract infections including bronchitis and pneumonia, otitis media and in upper respiratory tract infections including sinusitis and pharyngitis/tonsillitis, skin and soft tissue infections, mild to moderate typhoid due to multiple-antibacterial resistant organisms, cholera in children & adult and sexually transmitted diseases both in men and women. Azithromycin is also indicated for the treatment of uncomplicated genital infections due to Chlamydia trachomatis and urethritis and cervicitis due to Chlamydia trachomatis and Neisseria gonorrhoea
Warning & Precautions
As with any antibiotic preparation, observation for signs of superinfection with non-susceptible organisms, including fungi, is recommended. Caution should be exercised when Azithromycin is administered to subjects with severe renal impairment. Azithromycin is principally eliminated via the liver, so caution should be exercised when Azithromycin is administered to patients with impaired hepatic function.
Use in Pregnancy : Pregnancy category B.
Use in Lactation : Caution should be exercised when Azithromycin is administered to a nursing mother.
Side effects
AZ is well tolerated with a low incidence of side effects. Majority of the side effects are mild to moderate in nature and of gastro-intestinal in origin with nausea, abdominal discomfort, vomiting, flatulence and diarrhoea. Allergic reactions such as rash have occurred and there have also been rare reports of serious hypersensitivity reactions. Reversible elevations in liver transaminase have been seen with a frequency similar to the comparative macrolides and penicillins used in clinical trials.
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AZ 500mg 1pcs
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Description
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