Beclocort
Beclometasone Dipropionate
Beclometasone Dipropionate is a synthetic glucocorticoid. It has many important functions, including control of inflammatory responses. When Beclometasone is inhaled into the lungs, it is absorbed into the cells of the lungs and airways. By preventing the inflammation and excess mucus formation, Beclometasone makes it easier to breathe and helps prevent asthma attacks. Use of Beclometasone inhaler also reduces the potential for side effects occurring in other parts of the body, as the amount absorbed into the blood through the lungs is lower than if it is taken by mouth.
Indication:
Beclocort HFA inhaler is indicated in the maintenance treatment of asthma as prophylactic therapy in adults and children (5 years of age and above). It is also indicated for asthma patients who require systemic corticosteroid administration, where adding Beclometasone Dipropionate may reduce or eliminate the need for the systemic corticosteroids.
Beclometasone Dipropionate is not indicated for the relief of acute bronchospasm.
Dosage and administration:
Management of chronic asthma
Adults & children over 12 years: 100-400 µg twice daily. Maximum 1000 µg twice daily.
Children (5-12 years): 100-200 µg twice daily. Maximum 200-400 µg twice daily.
Prophylaxis of asthma
Adults & children over 12 years: 50-200 µg twice daily. Increased if necessary to maximum 400 µg twice daily.
Children (5-12 years): The usual starting dose is 100 µg twice daily. Depending on the severity of asthma, the daily dose may be increased up to 400 µg administered in 2-4 divided doses.
When patient’s symptoms remain under satisfactory control, the dose should be titrated to the lowest dose at which effective control of asthma is maintained.
Therapy in new patients:
Mild asthma: 50-100 µg twice daily.
Moderate asthma: 100-200 µg twice daily.
Severe asthma: 200-400 µg twice daily.
When switching a patient with well-controlled asthma from another corticosteroid inhaler, initially a 100 µg puff of Beclocort-100 HFA should be prescribed for-
200-250 µg of Beclometasone Dipropionate (CFC) or Budesonide.
100 µg of Fluticasone Propionate
When switching a patient with poorly controlled asthma from another corticosteroid inhaler, initially a 100 µg puff of Beclocort-100 HFA should be prescribed for 100 µg of Beclometasone Dipropionate (CFC) or Budesonide or Fulticasone Propionate. The dose of Beclocort HFA inhaler should be adjusted according to response.
Side effect:
Beclometasone Dipropionate HFA inhaler has been found generally well tolerated. The adverse effects that occurred in a very few patients are headache, pharyngitis, upper respiratory tract infection, rhinitis, sinusitis, pain, back pain, nausea, dysphonia etc. When taking Beclometasone Dipropionate, an occasional incidence of hoarseness and/or a rare occurrence of candidiasis of throat and mouth may occur; patients may find it helpful
to rinse out their mouth with water after using their inhaler to reduce the risk of candidiasis and hoarseness. Topical anti-fungal therapy can be used for the treatment of candidiasis while continuing treatment with Beclometasone Dipropionate. Special care is necessary in patients with active or quiescent pulmonary tuberculosis.
As with other inhaled therapy, paradoxical bronchospasm with wheezing may occur immediately after dosing. If it occurs, the preparation should be discontinued immediately and alternate therapy instituted. Systemic effects of inhaled corticosteroids may occur, particularly at high doses prescribed for prolonged periods. These may include adrenal suppression, growth retardation, decrease in bone mineral density in children and adolescents etc.
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