Indications
Consucon and Consucon MR is indicated for the treatment of type 2 diabetes mellitus.
Dosage & Administration
Consucon: The usual initial dose is 40 to 80 mg daily. The dose can be increased upto 320 mg daily in divided doses when needed. The drug should be taken before meal.
Consucon MR: The usual daily dosage is 1 to 4 tablets per day as a single dose. It is recommended that the drug should be taken at breakfast time. It is preferable to take this drug before breakfast in order to avoid or to minimize the possible onset of digestive disorders.
Side Effects
There may be hypoglycaemia in concurrent conditions such as hepatic and renal disease, malnutrition, alcohol intoxication. Sometimes headache, gastrointestinal upsets, nausea, dizziness, skin reactions including rash, pruritus, erythema may occur.
Precautions
Gliclazide should be used carefully in patients with hepatic impairment. If there is definite hepatic disease then gliclazide should not be used. Consucon (Gliclazide) can be used safely in patients with renal insufficiency as it is extensively metabolized. Consucon has less sudden hypoglycaemic episode than other sulfonylurea group of drugs.
Contraindications
Gliclazide should not be used in –
* Juvenile-onset (type – I) diabetes
* Diabetes associated with Ketosis
* Diabetic patients undergoing surgery, after severe injury or during infection
* Patients having hypersensitivity for sulfonylurea group of drugs
* Pregnant women and breast-feeding mother
* Hepatic insufficiency
Use in Pregnancy & Lactation
Pregnant Women: Gliclazide should not be used in pregnant women although animal studies of Gliclazide have not shown any teratogenic effect.
Nursing Mothers: This drug is contraindicated when breast feeding.
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