Indications
Clonazepam (Oral) is indicated in:
Anxiety disorders (Generalized, Phobic & Panic disorders)
Insomnia and sleep disturbances
Labile arterial hypertension
Peri and Post menopausal anxiety (Anxiety in middle aged women)
Burning Mouth Syndrome
Peri and Post menopausal anxiety (Anxiety in middle aged women)
Postoperative anxiety disorder
Post traumatic stress disorder
Anxiety in cancer patient (palliative treatment)
Tension Headache
Restless legs syndrome (RLS) or Wittmaack–Ekbom syndrome
Nocturnal myoclonus
Tourette’s syndrome
Bipolar affective disorder
Clonazepam (Injection) is indicated in:
- Epilepsy
- Status epilepticus
- Myoclonic seizure
- Typical and atypical absences (Lennox-Gastaut syndrome)
- Infantile spasm
- Tonic-clonic seizure
- Partial seizure
- Absence seizure
- Focal seizure
Therapeutic Class
Pharmacology
Dosage & Administration
Dosage must be determined in each patient according to clinical response and tolerance.
Oral:
Children: The initial dose for infants and children (up to 10 years of age or 30 kg of body weight) should be between 0.01 and 0.03 mg/kg/day and should not exceed 0.05 mg/kg/day given in two or three divided doses. Dosage should be increased by not more than 0.25 to 0.50 mg every third day until a maintenance dose of 0.1 to 0.2 mg/kg of body weight has been reached, unless seizures are controlled or side effects preclude further increase. Whenever possible, the daily dose should be divided into three equal doses. If doses are not equally divided, the larger dose should be given before retiring.
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