Erata 250mg 10pcs

Levetiracetam is indicated as an adjunctive therapy for:

• Partial Onset Seizures
• Myoclonic Seizures In Patients with Juvenile Myoclonic Epilepsy
• Primary Generalized Tonic-Clonic Seizures

Levetiracetam injection is an alternative for adult patients (16 years and older) when oral administration is temporarily not feasible.

For tablet and oral solution-

Treatment should be initiated with a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Additional dosing increments may be given (1000 mg/day additional every 2 weeks) to a maximum recommended daily dose of 3000 mg.

Injection-

Levetiracetam injection is for intravenous use only and must be diluted prior to administration. Levetiracetam injection (500 mg/5 mL) should be diluted in 100 mL of compatible diluents and administered intravenously as a 15-minute IV infusion. Product with particulate matter or discoloration should not be used.

Dosing Instructions: Preparation and Administration-

• Dose 500 mg: Withdraw Volume 5 ml, Volume of Diluent 100 ml, Infusion Time 15 minutes
• Dose 1000 mg: Withdraw Volume 10 ml, Volume of Diluent 100 ml, Infusion Time 15 minutes
• Dose 1500 mg: Withdraw Volume 15 ml, Volume of Diluent 100 ml, Infusion Time 15 minutes

For example, to prepare a 1000 mg dose, dilute 10 ml of Levetiracetam injection in 100 ml of a compatible diluents and administer intravenously as a 15-minute infusion.