Indications
Flutica Nasal Spray is indicated for the treatment of symptoms of seasonal and perennial allergic rhinitis in adults and children above 2 years and for the prevention of recurrence of nasal polyps following surgical removal.
Dosage & Administration
For intranasal use only. Adults and adolescents (12 years and over) The recommended starting dose is 2 sprays in each nostril once daily. Once adequate control of symptoms is achieved, dose reduction to one spray in each nostril once daily can be effective for maintenance.
Children (2 to 11 years of age): The recommended starting dose is 1 spray in each nostril once daily.
Precautions
Patients taking Fluticasone Furoate nasal spray should be periodically monitored for signs of adverse effects on the nasal mucosa such as epistaxis, nasal ulceration and impaired wound healing. Avoid using the drug in patients with recent nasal ulcers, nasal surgery, or nasal trauma. Closely monitor patients with a history of increased intraocular pressure, glaucoma and hypersensitivity reactions (including anaphylaxis, angioedema, rash, and urticaria). Besides, potential worsening of existing fungal, bacterial, viral, or parasitic infections or ocular herpes simplex, hypercorticism and growth retardation may occur after the administration of Fluticasone Furoate nasal spray.
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Contraindications
Fluticasone Furoate is contraindicated for the patients who have hypersensitivity to any components of this preparation. Side effects: The most common side effects are headache, epistaxis, pharyngolaryngeal pain, nasal ulceration, back pain, pyrexia, and cough.
Drug interaction
Potent inhibitors of cytochrome P450 3A4 (CYP3A4) may increase exposure to Fluticasone Furoate. Coadministration of ritonavir is not recommended. Use caution with coadministration of other potent CYP3A4 inhibitors, such as ketoconazole.
Special instruction: Patients should be instructed that the device must be primed: before first use, and if the cap is left off or if the device does not seem to be working or if the nasal spray has not been used for 30 days or more. In order to prime the device, the nasal spray needs to be shaken vigorously for about 10 seconds with the cap on. The patient must then press the button firmly all the way in, approximately 6 times until a fine mist is seen. Once primed, the patient must shake the nasal spray vigorously each time before use
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