COMPOSITION
LebacTM 250 capsule: Each capsule contains Cephradine USP 250 mg. LebacTM 500 capsule:
Each capsule contains Cephradine USP 500 mg. Lebac TM Powder for Suspension: After
reconstitution each 5 ml suspension contains Cephradine USP 125 mg. Lebac TM Forte
Powder for Suspension: After reconstitution each 5 ml suspension contains Cephradine USP
250 mg. LebacTM 500 mg IM/IV injection: Each vial contains Cephradine USP 500 mg.
LebacTM 1 gm IM/IV injection: Each vial contains Cephradine USP 1 gm. Lebac TM Paediatric Drops:
After reconstitution each 1.25 ml drops contains Cephradine USP 125 mg
- DOSAGE AND ADMINISTRATION
- The dosage may be given without regard to meals.
- Adult:
- Oral: The usual dose is 1-2 gm daily in 2 to 4 divided doses. In severe and prolonged
- infection, the dose can be increased up to 4 gm daily which should be taken in equally
- divided doses. Injection: The usual dose is 2-4 gm daily which should be given
- intramuscularly or intravenously in 3-4 divided doses. Special dose in the following infections
- Skin and skin structures and respiratory tract infection: Usual dose is 250 mg every 6 hours
or 500 mg every 12 hours. Lobar pneumonia: 500 mg every 6 hours or 1 gm every 12 hours.
Urinary tract infection: Usual dose is 500 mg every 12 hours. Gastro-intestinal tract infection:
500 mg three to four times daily.
SIDE EFFECT
Side effects include nausea, vomiting, diarrhoea and abdominal discomfort. Allergic
reactions including skin rashes, urticaria, eosinophilia, angioedema and anaphylaxis may
occur and elevation of hepatic enzyme values have been noted. Neutropenia has been
reported. Super-infection with resistant microorganisms, particularly candida, may follow the
treatment.There is also a possibility of development of pseudomembranous colitis.Transient
pain may be experienced at the injection site.Thrombophlebitis has been reported following
intravenous administrations
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