Indications
As a dietary supplement:
- Vitamin E deficiency resulting from impaired absorption.
- Increased requirements due to diet rich in polyunsaturated fats.
- For healthy hair & skin
- As an Antioxidant
- Hemolytic anemia due to Vitamin E deficiency
Therapeutic use: Heavy metal poisoning, Hepatotoxin poisoning, Hemolytic anemia, Oxygen therapy and replacement therapy in nutritional deficiency states for the betterment of skin and hair.
Therapeutic Class
Vitamin-E Preparations
Pharmacology
Vitamin E Capsule is a Vitamin E preparation. Vitamin E acts as an antioxidant in the body. Vitamin E protects polyunsaturated fatty acids (which are components of cellular membrane) and other oxygen-sensitive substances such as vitamin A & vitamin C from oxidation. Vitamin E reacts with free radicals, which is the cause of oxidative damage to cell membranes, without the formation of another free radical in the process. The main pharmacological action of vitamin E in humans is its antioxidant effect.In premature neonates irritability, edema, thrombosis and hemolytic anemia may be caused due to vitamin E deficiency. Creatinuria, ceroid deposition, muscle weakness, decreased erythrocyte survival or increased in vitro hemolysis by oxidizing agents have been identified in adults and children with low serum tocopherol concentrations.
Dosage & Administration
Betterment of Cardiovascular health: 400 mg – 800 mg / dayDeficiency syndrome in adults: 200 mg – 400 mg / day
Deficiency syndrome in children: 200 mg / day
Thalassemia: 800 mg / day
Sickle-cell anemia: 400 mg / day
Betterment of Skin & Hair: 200 mg – 400 mg / day (Topical use is also established for beautification)
Chronic cold in adults: 200 mg / day
Interaction
Vitamin E may impair the absorption of Vitamin A. Vitamin K functions impairement happens at the level of prothrombin formation and potentiates the effect of Warfarin.
Contraindications
No known contraindications found.
Side Effects
Overdoses (>1g) have been associated with minor side effects, including hypertension, fatigue, diarrhea and myopathy
Pregnancy & Lactation
Use in pregnancy:Â Vitamin E may be used in pregnancy in the normally recommended dose but the safety of high dose therapy has not been established.Use in lactation:Â There appears to be no contraindication to breast feeding by mothers taking the normally recommended dose.
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