Brand Name: Munil
Manufacturer : Opsonin Pharma Ltd
Indications
Bromhexine is indicated in the treatment of respiratory disorders associated with excessive mucus or productive cough. This include: Tracheobronchitis, Bronchitic with emphysema, Bronchiectasis, Bronchitis with bronchospasm, Chronic inflammatory pulmonary conditions, Pneumoconiosis
Therapeutic Class
Cough expectorants & mucolytics
Pharmacology
Bromhexine is an oral mucolytic agent with a low level of associated toxicity. It acts on the mucus at the formative stages in the glands, within the mucus-secreting cells. Bromhexine disrupts the structure of acid mucopolysaccharide fibres in mucoid sputum and produces less viscous mucus, which is easier to expectorate
Dosage & Administration
Tablet:
- Adults and children over 10 years: 8-16 mg 3 times daily.
- Children 5-10 years: 4 mg 3 times daily.
Syrup:
- Adults: The recommended daily dose is 2 to 4 teaspoonful 3 times. Initially 4 teaspoonful 3 times daily and then as required.
- Children: Suggested dosage for children under 2 years is 1/4 teaspoonful 3 times daily, for 2-5 years 1/2 teaspoonful 3 times daily and for children aged 5-10 years 1 teaspoonful 3 times daily.
Contraindications
Contraindicated to those who are hypersensitive to Bromhexine Hydrochloride.
Side Effects
Gastrointestinal side-effects may occur occasionally with Bromhexine and a transient rise in serum aminotransferase values has been reported. Other reported adverse effects include headache, dizziness, sweating and skin rash.
Pregnancy & Lactation
Pregnancy Category B. Bromhexine has been taken by a large number of pregnant women and women of child bearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus having been observed.
It is not known whether bromhexine is excreted in breast milk or whether it has a harmful effect on the breastfeeding infant. Therefore it is not recommended for breast feeding mothers unless the potential benefits to the patient are weighed against the possible risk to the infant.
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