Naprosyn® 250 Tablets: Each tablet contains Naproxen USP 250 mg.
Indications
Pharmacology
Dosage & Administration
General Onset of pain relief can begin within 1 hour in patients taking naproxen. A lower dose should be considered in patients with renal or hepatic impairment or in elderly patients. Naprosyn® is not recommended in patients with baseline creatinine clearance less than 10 ml/minute because accumulation of naproxen metabolites has been seen in such patients. Naprosyn® may be given orally either in fasting state or with meals and/or antacids. Dose in adults Chronic conditions: Osteoarthritis / Rheumatoid arthritis / Ankylosing spondylitis / chronic pain states in which there is an inflammatory component: The recommended dose of naproxen is Naprosyn® 250 mg or 500 mg taken twice daily (morning and evening), or a single daily dose of 500-1000 mg given in the morning or evening, or 500 mg taken twice daily, or a single daily dose of 1000 mg given in the evening. During long-term administration the dose of naproxen may be adjusted up or down depending on the clinical response of the patient. A lower daily dose may suffice for long-term administration. In patients who tolerate lower doses well, the dose may be increased to 1500 mg per day when a higher level of anti-inflammatory/analgesic activity is required. When treating patients with naproxen 1500 mg/day, the physician should observe sufficient increased clinical benefit to offset the potential increased risk (see Precautions). The morning and evening doses do not have to be equal in size and administration of the drug more frequently than twice daily does not generally make a difference in response. Acute conditions: Analgesia / Dysmenorrhoea / Acute musculoskeletal conditions/Acute pain states in which there is an inflammatory component: The recommended starting dose is Naprosyn® 500 mg followed by Naprosyn® 250 mg every 6-8 hours as required.
Interaction
Concomitant administration of antacid or cholestyramine can delay the absorption of naproxen , but does not affect its extent. Concomitant administration of food can delay the absorption of naproxen, but does not affect its extent. Naproxen is highly bound to plasma
Contraindications
Side Effects
Gastrointestinal: abdominal pain, constipation, diarrhea, dyspepsia, heartburn, nausea, stomatitis. Central nervous system: dizziness, drowsiness, headache, lightheadedness, vertigo. Dermatologic: ecchymoses, itching (pruritus), purpura, skin eruptions, sweating. Cheap for sale online, high quality louboutin. Special senses: hearing disturbances, tinnitus, visual disturbances. Cardiovascular: dyspnea, edema, palpitations. General: thirst.
Pregnancy & Lactation
Pregnancy: As with other drugs of this type, naproxen produces delay in parturition in animals and also affects the human fetal cardiovascular system (closure of ductus arteriosus). Therefore, naproxen should not be used during pregnancy unless clearly needed.
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