Indication:
Omep Capsule
Omep is indicated for short and long term treatment of duodenal ulcer, gastric ulcer, resistant ulcer, NSAIDs-induced peptic ulcer and gastroduodenal erosions, erosive reflux esophagitis, refractory reflux esophagitis, acid reflux disease, acid related dyspepsia, Zollinger-Ellison syndrome.
Omep IV Injection :
Prophylaxis of acid aspiration.
Treatment in patients where oral therapy is inappropriate e.g. in severely ill patients with reflux esophagitis, duodenal ulcer, gastric ulcer etc.
Zollinger-Ellison syndrome.
Dosage & Administration
Omep Capsule :
Omep capsule should be taken before meal.
Duodenal ulcer : 20 mg once daily for 4 weeks. In severe cases 40 mg once daily for 4 weeks.
Gastric ulcer : 20 mg once daily for 8 weeks. In severe cases 40 mg once daily for 8 weeks.
Resistant ulcer : 40 mg daily for 4 weeks. For long term therapy the maintenance dose is 40 mg daily.
Maintenance of recurrent duodenal ulcer : 20 mg once daily.
NSAIDs induced peptic ulcer and gastroduodenal erosions : 20 mg once daily for 4 weeks, followed by a further 4 weeks if not fully healed. Prophylaxis in patients with a history of NSAIDs associated gastroduodenal lesions that require continued NSAIDs treatment, 20 mg once daily.
Gastro Esophageal Reflux Disease (GERD) : Adult: 20 mg once daily for 4 weeks, continued for further 4-8 weeks if not fully healed. Children aged 1-16 years: Body weight 10 Kg to <20 Kg: 10 mg once daily for 4-8 weeks & 20 Kg: 20 mg once daily for 4-8 weeks.
Refractory reflux esophagitis : 40 mg once daily for 8 weeks, may be continued at 20 mg once daily.
Acid reflux disease : For long term management, 10 mg daily, increasing to 20 mg once daily if symptoms return.
Acid related dyspepsia : 10-20 mg once daily for 2-4 weeks according to response.
Zollinger-Ellision Syndrome : 60 mg once daily adjusted individually and continued as long as necessary. Most patients will be effectively controlled with 20-120 mg daily. Dosage above 80 mg should be divided and given twice daily.
Side effcet:
Omep is generally well tolerated. Nausea, diarrhoea, flatulence, abdominal pain, constipation, dizziness and headache have been stated to be generally mild and transient and not requiring a reduction in dosage.
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