Indication
Optimox is indicated for treating the following infections caused by susceptible bacteria. 1. Community acquired pneumonia 2. Exacerbation of chronic bronchitis 3. Sinusitis 4. Skin and soft tissue infections 5. Pelvic inflammatory disease 6. Complicated intra-abdominal infections 7. Hospital-acquired pneumonia 8. Infective endocarditis etc.
Dosage & Administration
The recommended dose of Optimox is 400 mg once daily. The duration of therapy depends on the type of infections. Community Acquired Pneumonia 400 mg once daily for 7-14 days, Exacerbation of chronic bronchitis 400 mg once daily for 5-10 days, Sinusitis 400 mg once daily for 7-10 days, Skin and soft tissue infections 400 mg once daily for 7-21 days, Pelvic inflammatory diseases 400 mg once daily for 14 days, Complicated intra-abdominal infections 400 mg once daily for 5-14 days, Hospital-acquired pneumonia 400 mg once daily for 7-8 days, Infective endocarditis 400 mg once daily for 28-42 days. No dosage adjustment is required in patients with renal or hepatic impairment.
Contraindications
Optimox is contraindicated in the patients with known hypersensitivity to Moxifloxacin or other quinolones.
Side effects
Most side effects reported with Moxifloxacin treatment are mild to moderate in nature and require no treatment. Most common adverse reactions are nausea, diarrhea, headache and dizziness.
Drug interaction
Antacids, sucralfate, multivitamins and other products containing multivalent cations reduces the absorption of Moxifloxacin. Moxifloxacin should be administered 4 hours before or 8 hours after antacids, sucralfate, multivitamins and other products with multivalent cations. It may enhance anticoagulant effect of warfarin and proarrythmic effect of Class IA and Class III antiarrhythmics. So concomitant use of Moxifloxacin with them should be avoided. No clinically significant drug interactions of theophylline, digoxin, or glyburide have been observed with Moxifloxacin.
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