Indications
Therapeutic Class
Pharmacology
Dosage & Administration
The recommended dose of Co-enzyme Q10 is:
For Co-enzyme Q10 deficiency:Â 150 mg daily.
For mitochondrial disorders:Â 150-160 mg, or 2 mg/kg/day.
For heart failure in adults:Â 100 mg per day divided into 2 or 3 doses.
For recent myocardial infarction:Â 120 mg daily in 2 divided doses.
For high blood pressure:Â 120-200 mg per day divided into 2 doses.
For isolated systolic hypertension:Â 60 mg twice daily.
For preventing migraine headache:Â 100 mg three times daily.
For Parkinsons disease:Â 300 mg, 600 mg, 1200 mg and 2400 mg per day in 3-4 divided doses.
For infertility in men:Â 200-300 mg per day.
For muscular dystrophy:Â 100 mg per day.
Dividing the total daily dose by taking smaller amounts two or three times a day instead of a large amount all at once can help to reduce side effects.
Interaction
Warfarin: Supplemental Coenzyme Q10 may decrease the effectiveness of Warfarin.
Statins: The statin drugs are known to decrease Coenzyme Q10 levels in humans.
Doxorubicin: Coenzyme Q10 may increase the cardiotoxicity of doxorubicin.
Antidiabetic medications: Coenzyme Q10 may improve glycemic control in some type II diabetics. If this were to occur, antidiabetic medications might need appropriate adjusting
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