Qcin 300mg 1pcs

Indications
Clindamycin has been shown to be effective in the treatment of the following infections when caused by susceptible anaerobic bacteria or susceptible strains of gram positive bacteria such as Streptococci, Staphylococci and Pneumococci;
 Upper respiratory infections,
 Lower respiratory infections,
 Skin and soft tissue infections,
 Bone and joint infections,
 Diabetic foot infections,
 Pelvic infections,
 Intra-abdominal infections,
 Septicemia and endocarditis,
 Dental infections.
As an alternative therapy when used in combination with quinine or amodiaquine for the treatment of multi-drug resistant Plasmodium falciporum infection.

Dosage and Administration
Dosage of Qcin® Capsule
Serious infections: 150mg – 300mg every 6 hours.
More severe infections: 300mg – 450mg every 6 hours.
To avoid the possibility of oesophageal irritation, Qcin® capsules should be taken with a full glass of water. Several researches have found that Clindamycin 300mg capsule provides plasma concentration over MIC90 for more than 12 hours. These finding supports the twice daily dosing of Qcin® 300mg capsule particularly in SSTls & RTls.
However, incase of bone & joint infections, diabetic foot infections dose of Clindamycin should be 300mg capsule 3-4 times daily. Pathogens Duration of Plasma conc. remains over MIC90

Side-effects
The adverse effects have been reported with the use of Clindamycin areabdominal pain, oesophagitis and oesophageal ulcer, nausea, vomiting and diarrhoea, pruritus, skin rashes, urticaria.

Precautions
Qcin should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.

Use in pregnancy & lactation
Pregnancy
Pregnancy category B: Clindamycin crosses the placenta in humans. After multiple doses, amniotic fluid concentrations were approximately 30% of maternal concentrations. Clindamycin should be used in pregnancy only if learly needed.