Ryzodeg FlexTouch Pen
Generic Name: insulin aspart and insulin degludec (IN su lin AS part and IN su lin de GLOO dek)
Brand Names: Ryzodeg 70/30 FlexTouch
Medically reviewed on June 15, 2016.
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What is Ryzodeg?
Ryzodeg contains a combination of insulin aspart and insulin degludec. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin aspart is a fast-acting insulin. Insulin degludec is a long-acting insulin. This combination insulin starts to work within 10 to 20 minutes after injection, peaks in about 1 hour, and keeps working for 24 hours or longer.
Ryzodeg is used to improve blood sugar control in adults with diabetes mellitus.
Ryzodeg may be used for type 1 or type 2 diabetes.
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Important information
You should not use Ryzodeg if you are having an episode of hypoglycemia (low blood sugar).
Never share a Ryzodeg injection pen with another person, even if the needle has been changed.
Before taking this medicine
You should not use Ryzodeg if you are allergic to insulin aspart or insulin degludec, or if you are having an episode of hypoglycemia (low blood sugar).
Ryzodeg is not approved for use by anyone younger than 18 years old.
To make sure Ryzodeg is safe for you, tell your doctor if you have:
liver or kidney disease;
low levels of potassium in your blood (hypokalemia); or
diabetic ketoacidosis (call your doctor for treatment).
Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using Ryzodeg may increase your risk of serious heart problems.
Follow your doctor’s instructions about using Ryzodeg if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy.
Ask your doctor about using Ryzodeg if you are breast-feeding a baby. Your dose needs may be different while you are nursing.
Ryzodeg side effects
Get emergency medical help if you have signs of an allergic reaction to Ryzodeg: hives, itching, skin rash; wheezing, tiredness, trouble breathing; feeling like you might pass out; nausea, diarrhea; swelling of your face, lips, tongue, or throat.
Call your doctor if you have:
fluid retention – weight gain, swelling in your hands or feet, feeling short of breath; or
low potassium – leg cramps, constipation, irregular heartbeats, fluttering in your chest, extreme thirst, increased urination, numbness or tingling, muscle weakness or limp feeling.
Common Ryzodeg side effects may include:
low blood sugar;
itching, mild skin rash; or
thickening or hollowing of the skin where you injected the medicine.
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