Indication
Sinaceph is indicated for the following diseases:
Skin and soft tissue infection: Abscess.cellulitis, furunculosis. Impetigo. Urinary tract infection: Cystitis, urethritis,
pyelonephritis.
Upper and lower respiratory tract infection: Pharyngitis, sinusitis, otitis media, tonsIlitis, acute and r:hronic
bronchitis, lobar and bronchopneumonia. Gastrointestinal infection: Bacillary dysentery, enteritis, peritonitis.
Genital infection, Bones and joint infection, Nose, ear and throat infection, Post operative infection and infections
caused by sensitive microorganism of Cephradine.
Dosage & Administration
Oral: Adult: For respiratory and soft tissue infections in adults, the usual dose, is 250 oar 500 mg four times daily. For
urinary tract infection, the usual dose is 500 mg four tunes daily. For gastrointestinal infection, the usual dose is 500
mg three to four times daily. J:; to 1 gm four times daily may be given for severe or chronic infection, Children: The
usual dose is 25-50 mgikglday given in 2 to 4 equally divided doses. For the treatment of otitis media the dose is 75-
100 mg./kg daily in 2 to 4 equally divided doses The total daily ucse should not exceed 4 gm.
Parenteral: Adult: The usual dose is 2- :n ia,ly in four equally divided doses up to S gin daily. For prophylaxis, a single
preoperative dose of 1-2 gm intramuscularly or intravenously is given. Children: The dose is 50-100 rnglkg
daily in four equally divided doses. up to 300 mg/kg daily in severe infection.
Side effect
Nausea, vomiting, diarrhoea and abdominal discomfort may occur.
Contraindication
Cephradine is contraindicated to patients who are hypersensitive to Cephalosporin group of antibiotics.
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