Brand Name: TCL-R
Manufacture: Aristopharma Ltd.
Indications
– Reduce the risk of MI, stroke, revascularization procedures and angina in patients without CHD, but with multiple risk factors.- Reduce the risk of MI and stroke in patients with type 2 diabetes without CHD, but with multiple risk factors.– Reduce the risk of non-fatal MI, fatal and non-fatal stroke, revascularization procedures, hospitalization for CHF, and angina in patients with CHD.
Pharmacology
Cyclosporine, HIV protease inhibitors (tipranavir plus ritonavir saquinavir plus ritonavir, hepatitis C protease inhibitor (telaprevir): Avoid Atorvastatin. HIV protease inhibitor (lopinavir plus ritonavir): Use with caution and lowest dose necessary.Clarithromycin,itraconazole, HIV protease inhibitors (saquinavir plus ritonavir,darunavir plus): Do not exceed 20 mg Atorvastatin daily. HIV protease inhibitor (nelfinavir), Hepatitis C protease inhibitor (boceprevir): Do not exceed 40 mg Atorvastatin daily.
Side Effects
Atorvastatin is generally well tolerated. Side effects reported commonly include constipation, flatulence, dyspepsia, abdominal pain, headache, nausea, myalgia, diarrhoea, asthenia and insomnia. Others include muscle cramps, paresthesia, pancreatitis, hepatitis, cholestatic, anorexia, vomiting, pruritus, rash.
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