Brand Name: Unipril 2.5
Manufacturer: Acme Laboratories Ltd.
Indication :Â Mild to severe hypertension, Congestive heart failure, to reduce the risk of stroke, myocardial infarction and death from cardiovascular events, Proteinuric non-diabetic nephropathy.
Dosage & Administration :Â Hypertension : 1.25-2.5 mg once daily. Maintenance dosage in adults is 2.5-20 mg daily given as a single dose or in 2 divided doses daily. Congestive Heart failure after myocardial infarction : Initiated as early as 2 days after myocardial infarction. An initial dose 2.5 mg twice daily is recommended, but if hypotension occurs, dose should be reduced to 1.25 mg twice daily. Therapy is then titrated to a target daily dose of 5 mg twice daily. Prevention of major cardiovascular events: 2.5 mg once daily for the first week of therapy and 5 mg once daily for the following 3 weeks; dosage then may be increased, as tolerated, to a maintenance dosage of 10 mg once daily. Dosage in renal impairment : 1.25 mg once daily. Subsequent dosage should be titrated according to individual tolerance and blood pressure response, up to a maximum of 5 mg daily. Heart failure and renal impairment : 1.25 mg once daily. The dose may be increased to 1.25 mg twice daily and up to a maximum dose of 2.5 mg twice daily depending upon clinical response and tolerability.
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