Laxyl® is indicated for the treatment of anxiety & anxiety related to disorders
Emotional disturbance: Acute tension and anxiety states. Difficulties in
interpersonal contact. Agitation, insomnia, anxious and agitated depressive
Functional disturbance in the cardiovascular and respiratory systems:
Pseudoangina pectoris, precordial anxiety, tachycardia, emotiogenic
hypertension, dyspnea and hyperventilation.
Functional disturbance in the gastrointestinal system: Irritable bowel
syndrome, epigastric pain, spasm, bloting diarrhoea, etc.
Functional disturbance in the genitourinary system: Frequency, Irritable
bladder, and dysmenorrhea.
Psychosomatic disorders: Psychogenic headache, psychogenic dermatosis,
asthma, gastric & duodenal ulcer, and ulcerative colitis. Emotional reactions
to chronic organic disease. Adjuvant to psychotherapy in psychoneurosis.
Patients with known sensitivity to benzodiazepines; acute pulmonary
insufficiency; respiratory depression; phobic or obsessional states; chronic
Common adverse effects include drowsiness, sedation, unsteadiness and
ataxia; these are dose-related and may persist into the following day, even
after a single dose. Drowsiness may be a particular problem when
Bromazepam is used in higher dosage in some patients, especially if they
are unused to this form of therapy. The elderly are particularly sensitive to
the effects of centrally depressant drugs and may experience confusion;
especially if organic brain changes are present; the dosage of Bromazepam
should not exceed one-half that recommended for other adults. Other
adverse effects are rare and include headache, vertigo, hypotension, gastrointastinal
upsets, skin rashes, visual disturbances, changes in libido, and
urinary retention. Isolated cases of blood dyscrasias and jaundice have also
USE IN PREGNANCY AND LACTATION
There is no evidence as to drug safety in human pregnancy, nor is there
evidence from animal work that it is free from hazard. Do not use during
pregnancy, especially during the first and last trimesters, unless there are
compelling reasons. The administration of high doses or prolonged
administration of low doses of benzodiazepines in the last trimester of
pregnancy has been reported to produce irregularities in the foetal heart
rate, and hypotonia, poor sucking and hypothermia in the neonate.
Benzodiazepines have been detected in breast milk. If possible, the use of
Bromazepam should be avoided during lactation.