Indications
Clonazepam (Oral) is indicated in:
- Anxiety disorders (Generalized, Phobic & Panic disorders)
- Insomnia and sleep disturbances
- Labile arterial hypertension
- Peri and Post menopausal anxiety (Anxiety in middle aged women)
- Burning Mouth Syndrome
- Peri and Post menopausal anxiety (Anxiety in middle aged women)
- Postoperative anxiety disorder
Clonazepam (Injection) is indicated in:
- Epilepsy
- Status epilepticus
- Myoclonic seizure
- Typical and atypical absences (Lennox-Gastaut syndrome)
- Infantile spasm
- Tonic-clonic seizure
- Partial seizure
- Absence seizure
- Focal seizure
Therapeutic Class
Pharmacology
Dosage & Administration
Dosage must be determined in each patient according to clinical response and tolerance.
Infants and children: half of a vial (0.5 mg) by slow IV injection or by IV infusion.
Adults: 1 vial (1 mg) by slow IV injection or by IV infusion. This dose can be repeated as required (1-4 mg are usually sufficient to reverse the status). In adults, the rate of injection must not exceed 0.25 – 0.5 mg per minute (0.5-1.0 ml of the prepared solution) and a total dose of 10 mg should not be exceeded.
Slow intravenous injection: The contents of the vial must be diluted with 1 ml of water for injection prior to administration so as to avoid local irritation of the veins. The injection solution should be prepared immediately before use. IV injection should be administered slowly with continuous monitoring of EEG, respiration and blood pressure.
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