INDICATION :
Moxacil®
is indicated in the treatment of infections due to susceptible strains of the designated
microorganisms in the condition listed below:
Infections of the ear, nose, and throat due to streptococcus spp.(α- and β-hemolytic strains
only), S. pneumoniae,Staphylococcus spp., or H. influenzae
Infections of the genitourinary tract due to E. coli, P. mirabilis, or E. faecalis
Infections of the skin and skin structure due to Streptococcus spp.( α- and β-hemolytic strains
only), Staphylococcus spp., or E. coli
Infections of the lower respiratory tract due to Streptococcus spp.( α- and β-hemolytic strains
only), S. pneumoniae, Staphylococcus spp., or H. influenzae
Gonorrhea, acute uncomplicated (ano-genital and urethral infections) due to N. gonorrhoeae (male
and females). H. pylori eradication to reduce the risk of duodenal ulcer recurrence in combination
with clarithromycin plus lansoprazol as triple therapy.
Moxacil®
may also be used as prophylactic cover for patients at risk of developing endocarditis
when undergoing dental surgery.
RECONSTITUTION & ADMINISTRATION :
Moxacil® Suspension / Moxacil® Forte Suspension:
Shake the bottle well before adding water. Then add 12 tea spoonful (60 ml) of boiled and cooled
water to the bottle and shake well to make 100 ml suspension.
Moxacil®
500 Injection:
Intramuscular : Add 2.5 ml water for injection to Moxacil®
500 injection vial.
Intravenous : Dissolve Moxacil®
500 injection in 10 ml water for injection.
CONTRAINDICATION:
It is contraindicated for patients hypersensitive to penicillin.
PRECAUTION:
In renal impairment the excretion of antibiotic will be delayed and depending on the degree of
impairment it may be necessary to reduce the total daily dose. Caution should also be exercised in
case of erythematous rashes, glandular fever, history of allergy etc.
ADVERSE EFFECTS:
Adverse effects are mild, rare and infrequent. As with other penicillins it may induce diarrhoea,
indigestion or skin rashes which usually stop during treatment and rarely calls for discontinuation of
therapy.
USE IN PREGNANCY & LACTATION :
Because of its lack of teratogenicity, amoxycillin can be used safety throughout pregnancy at the
normal adult dose. The small amount of amoxycillin secreted in maternal milk rarely causes
problems in the infant. It can therefore be used safety during lactation in most instances.
DRUG INTERACTION :
Concurrent administration of probenecid delays the excretion of amoxycillin.
STORAGE: protect from light and moisture, store in a cool and dry place
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