Brand Name: Myoson
Manufacturer: Ibn-Sina Pharmaceuticals Ltd.
Indications
Treatment of painful musculoskeletal disorders with hypermyotonia and decreased motility, especially those resulting from spinal cord injuries, osteoporosis, arthritis, and spasticity. It has also been effective in lumboischial pain, neurolathyrism, knee arthritis, peripheral circulatory diseases, climacteric muscular and vascular complaints, trismus, myogenous headaches, rheumatic diseases accompanied by muscular hypertonia, spasms, pain, inflammatory symptoms and limited motion, and in the post-surgical treatment of traumatologic patients.
Therapeutic Class
Central Depolarizing muscle relaxants, Centrally acting Skeletal Muscle Relaxants
Description
Tolperisone Hydrochloride is a centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation and reduces pain
Pharmacology
Tolperisone is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channels
Dosage & Administration
Adult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.
Children:
3 months to 6 years: 1-2 mg/kg/day in 3 divided doses.
6 years to 14 years: 2-4 mg/kg/day in 3 divided doses
Interaction
Concomitant use of Methocarbamol with Tolperisone Hydrochloride has been reported to cause disturbance of visual accommodation.
Contraindications
Hypersensitivity, Myasthenia Gravis and nursing mother.
Side Effects
Diarrhea, dizziness, drowsiness, dryness of the mouth, fall of blood pressure, fatigue, gastric complaints, headaches, hypersensitivity, itching, muscle pain, muscle weakness, rash, and somnolence.
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