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HomeMedicineTablet Nexum 20mg 10pcs
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Nexum MUPS 40 6pcs ৳ 60

Nexum 20mg 10pcs

৳ 70

Categories: Medicine, Tablet Brand: SQUARE PHARMACEUTICALS LTD
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Description

Indications

Esomeprazole is indicated:

  • Treatment of Gastroesophageal Reflux Disease (GERD)
  • Healing of Erosive Esophagitis
  • Maintenance of Healing of Erosive Esophagitis
  • Symptomatic Gastroesophageal Reflux Disease
  • H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
  • Zollinger-Ellison Syndrome
  • Acid Related Dyspepsia
  • Duodenal and Gastric Ulcer

Therapeutic Class

Proton Pump Inhibitor

Pharmacology

Esomeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in the gastric parietal cell. It is the S-isomer of omeprazole.

Dosage

Tablet:

Healing of erosive esophagitis: 20 mg or 40 mg once daily for 4 to 8 Weeks. For those patients who have not healed after 4-8 weeks of treatment, an additional 4-8 weeks course of Esomeprazole may be considered.

Long-term management of esophagitis: 20 mg once daily.

Symptomatic gastroesophageal reflux disease: 20 mg once daily for 4 weeks.

H. pylori eradication for treatment of duodenal ulcer: Triple therapy: 20 mg Esomeprazole once daily with 500 mg Clarithromycin twice daily, and 1 g Amoxicillin twice daily for 7-10 days.

Injection:

The recommended adult dose in GERD with Erosive Esophagitis is either 20 or 40 mg Esomeprazole given once daily by intravenous injection (no less than 3 minutes) or intravenous infusion (10 to 30 minutes).

Pediatric dose (1 to 11 years old):

  • Short term treatment of symptomatic GERD: 10 mg once daily for up to 8 weeks.

Healing of erosive esophagitis:

  • Weight <20 kg: 10 mg once daily for up to 8 weeks.
  • Weight ≥20 kg: 10 mg or 20 mg once daily for up to 8 weeks.

Administration

Preparations for Use and Administration of Esomeprazole 40 IV Injection: A solution for intravenous infusion is prepared by first reconstituting the contents of one vial with 5 ml of 0.9% Sodium Chloride and further diluting the resulting solution to a final volume of 50 ml. The resultant concentration after diluting to a final volume of 50 ml is 0.8 mg/ml.

  • 20 mg dose: Withdraw 25 ml of the final solution and administer as an intravenous infusion over 10 minutes to 30 minutes.
  • 10 mg dose: Withdraw 12.5 ml of the final solution and administer as an intravenous infusion over 10 minutes to 30 minutes.

Pregnancy: There are no adequate and well-controlled studies on the use of Esomeprazole in pregnant women. Therapeutic doses during pregnancy are unlikely to pose a substantial teratogenic risk. Esomeprazole should be used during pregnancy only if the potential benefit to pregnant women justifies the potential risk to the fetus.

Lactation: Esomeprazole is excreted in human milk. Thus, a decision should be taken to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

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Nexum 20mg 10pcs

৳ 70