Presentation
Sultolin® Respirator Solution is an aqueous colourless solution of Salbutamol
Sulphate BP adjusted with acid pH 3.5. Each millilitre of the solution contains
5 mg of Salbutamol BP.
Indication
Sultolin® Respirator Solution is indicated for the treatment of severe acute
asthma (status asthmaticus) and also forms of bronchospasm.
Dosage Administration
By Intermittent Administration
Adult: Sultolin Respirator Solution 0.5-4.0 ml should be diluted to final volume
of 2.0-4.0 ml with normal saline for injection. The resulting solution is inhaled
from a suitably driven nebuliser until aerosol generation ceases. Using a
correctly matched nebuliser and driving source this should take about 10
minutes.
Sultolin® Respirator Solution may be used undiluted for intermittent
administration. For this 2.0 ml of the solution is placed in the nebuliser and the
patient allowed to inhale until bronchodilatation is achieved. This usually takes
3-5 minutes. Some adult patients may require higher doses of salbutamol upto
10 mg in which case nebulisation may continue until aerosol generation
ceases.
Children under 12 years age: 0.5 ml of the solution diluted to 2.0-4.0 ml with
normal saline. Some children may however require higher doses of upto 1.0
ml of the solution. Intermittent treatment may be repeated four times a day.
By Continuous Administration: Sultolin Respirator Solution is diluted with
normal saline for injection, 1-2 ml solution made upto 100 ml with diluent. The
diluted solution is administered as an aerosol by a suitably driven nebuliser.
The usual rate of administration is 1-2 mg/hour. Delivery of the aerosol may be
by face mask or via an endotracheal tube. Intermittent positive pressure may
be used but is rarely necessary. When there is risk of anoxia through
hypoventilation, oxygen should be added to the inspired air.
Contra-Indication & Precautions: History of hypersensitivity to any of its
components. Sultolin presentation should not be used for threatened abortion
during the first or second trimester of pregnancy.
It should be used with care in patients known to have received large doses of
other sympathomimetic drugs.
It should be used with care in patients suffering from thyrotoxicosis. Sultolin
Respirator Solution should be used with a respirator or nebuliser, only under
the direction of a physician. Not to be injected, or taken orally.
Patients receiving treatment at home with Sultolin Respirator Solution should
be warned that if either usual relief is diminished or the usual duration of
action reduced, they should not increase the dose or its frequency of
administration but seek medical advice.
Use in Pregnancy: Unnecessary administration of drugs during the first
trimester of pregnancy is undesirable.
Side Effect: A small increase in heart rate may occur in patients who inhale
large doses of Sultolin. This is not usually accompanied by any changes in
ECG. Other side effects which occur with high doses are peripheral
vasodilation and fine tremor of skeletal muscle.
Overdosage: During continuous administration any signs of overdosage may
be counteracted by withdrawal of the drug. The preferred antidote for
overdosage is a cardioselective betablocker, but betablockers should be used
with caution in patients with a history of bronchospasm.
Pharmaceutical precautions: Store at a cool & dry place, protected from
light. Once a bottle has been opened the contents should be discarded after
one month.
For use only under the presentation of a registered physician.
Dilution: Sultolin® Respirator Solution may be diluted with Sodium Chloride
Injection MP (normal saline). Solutions in nebulisers should be replaced daily.
How supplied:
Sultolin® Respirator Solution: Each bottle contains 20 ml respirator Solution.
Sultolin 200mcg 6pcs
৳ 15
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