Zemicef 200 Capsule: Each capsule contains Cefixime USP equivalent to 200 mg Anhydrous Cefixime. Zemicef 400 Capsule: Each capsule contains Cefixime USP equivalent to 400 mg Anhydrous Cefixime. Zemicef Powder for Suspension: Each 5 ml suspension contains Cefixime USP equivalent to 100 mg Anhydrous Cefixime. ZemicefDS Powder for Suspension: Each 5 ml suspension contains Cefixime USP equivalent to 200 mg Anhydrous Cefixime.
Dosage and administration:
Adult: 1 or 2 capsules (200-400 mg) as once or in 2 divided doses daily for 7-14 days, according to the severity of the infection. Children above 6 months: 8 mg per kg body weight as a single dose or in two divided doses for 7-14 days according to the severity of the infection or as following: 6 months-1 year: 75 mg/day 1-4 years: 100 mg/day 5-10 years: 200 mg/day 11-12 years: 300 mg/day Above 12 years: Adult dose may be administered. Efficacy and safety in infants aged less than six months have not been established.
Side effect:
Cefixime is generally well tolerated. The majority of adverse reactions observed in clinical trials was mild and self-limiting in nature. Gastro-intestinal disturbances: such as Diarrhoea (if severe diarrhoea occurs, Cefixime should be discontinued), changes in the color of stool, nausea, abdominal pain, dyspepsia, vomiting, flatulence have been reported. Central nervous system disturbances: Headache, dizziness, etc. Others: Hypersensitivity reactions which usually subsided upon discontinuation of therapy; infrequent and reversible haematological changes; elevation of serum amylase, etc.
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